The presenting clinical picture is frequently pharyngitis, fever, and. Waterhousefriderichsen syndrome, also known as hemorrhagic adrenalitis, is a condition that describes acute adrenal failure, caused by hemorrhage within the adrenal glands after a severe bacterial infection, in particular meningococcal disease. Waterhousefriderichsen syndrome pathology britannica. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Seventyfour such cases have been described in the literature. The onset of the illness is nonspecific with fever, rigors, vomiting, and headache. Neisseria meningitidis cause a fulminating fatal infection, frequently with few or no signs or preconditions. Waterhousefriderichsen syndrome definition of waterhouse. Septic shock caused by waterhousefriderichsen syndrome.
When caused by neisseria meningitidis, wfs is considered the most severe form of meningococcal sepsis. The waterhouse friderichsen syndrome is a clinical entity first described in 1911 by waterhouse 1 in an eightmonthold child. Waterhouse friderichsen syndrome, meningococcal, septic shock. The waterhousefriderichsen syndrome is a clinical entity first described in 1911 by waterhouse 1 in an eightmonthold child. Waterhouse friderichsen syndrome wfs is a group of symptoms resulting from the failure of the adrenal glands to function normally as a result of bleeding into the gland. Waterhousefriderichsen, meningococo, shock septico, waterhousefriderichsen syndrome, meningococcal, septic shock, lcc. Waterhousefriderichsen syndromemassive adrenal haemorrhage in the setting of overwhelming clinical sepsisis usually taken at necropsy to indicate meningococcal infection, and may be the only. Waterhouse friderichsen syndrome waterhousefriderichsen. Meningococcemia is a lifethreatening infection that occurs when the bacteria neisseria meningitidis invades the blood stream. Waterhouse friderichsen syndrome also known as purpura fulminans 9 or hemorrhagic adrenalitis 10 is characterized by adrenal insufficiency that results from atraumatic adrenal hemorrhage in consequence of septicemia. Aldosteronismo primario sintomas y causas mayo clinic. All structured data from the file and property namespaces is available under the creative commons cc0 license. Files are available under licenses specified on their description page. Medical definition of waterhousefriderichsen syndrome.
There is bleeding into the adrenal glands causing adrenal failure and shock. Feb 01, 2017 septic shock caused by neisseria meningitidis infection, defined as waterhouse friderichsen syndrome in 1946, has a high mortality rate of between 21% and 44%. An exceptional case of a 15yearold puerpera with septic shock caused by group a. Waterhouse friderichsen syndrome, a rare type of septicemia blood poisoning of rapid and severe onset, marked by fever, collapse and sometimes coma, hemorrhage from skin and mucous membranes, and severe bilateral hemorrhage of the adrenal cortical tissue. Waterhouse friderichsen syndrome waterhouse friderichsen syndrome. Apr 03, 20 definition waterhousefriderichsen syndrome wfs or hemorrhagic adrenalitis or fulminant meningococcemia, is defined as adrenal gland failure due to bleeding into the adrenal glands, caused by severe bacterial infection most commonly the meningococcus neisseria meningitidis. A case of a patient with the waterhousefriderichsen syndrome has been described. Waterhousefriderichsen syndrome information mount sinai. Waterhousefriderichsen syndrome radiology reference.
Staphylococcus aureus sepsis and the waterhouse friderichsen. Waterhouse friderichsen syndrome can be caused by a number of different organisms see below. Waterhousefriderichsen, meningococo, shock septico. Waterhousefriderichsen syndrome medical definition. Fulminating meningococcemia with bilateral adrenal hemorrhage. The disease now known as the waterhouse friderichsen syndrome was recognized as an entity by little1 in 1901. The condition is most frequently seen in children younger than 10 years old.
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